Partial volume correction analysis for 11C-UCB-J PET studies of Alzheimer's disease

Purpose: 11C-UCB-J PET imaging, targeting synaptic vesicle glycoprotein 2A (SV2A), has been shown to be a useful indicator of synaptic density in Alzheimer's disease (AD). For SV2A imaging, a decrease in apparent tracer uptake is often due to the combination of gray-matter (GM) atrophy and SV2A...

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Bibliographic Details
Main Authors: Yihuan Lu, Takuya Toyonaga, Mika Naganawa, Jean-Dominique Gallezot, Ming-Kai Chen, Adam P. Mecca, Christopher H. van Dyck, Richard E. Carson
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:NeuroImage
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811921005255