Matrine promotes mitochondrial biosynthesis and reduces oxidative stress in experimental optic neuritis

Optic neuritis (ON), characterized by inflammation of the optic nerve and apoptosis of retinal ganglion cells (RGCs), is one of the leading causes of blindness in patients. Given that RGC, as an energy-intensive cell, is vulnerable to mitochondrial dysfunction, improving mitochondrial function and r...

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Bibliographic Details
Main Authors: Yifan Song, Mengru Wang, Suyan Zhao, Yanjie Tian, Chun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.936632/full