Philadelphia chromosome positive AML arising from JAK2-positive myelofibrosis

Philadelphia chromosome positive AML arising from JAK2-positive myelofibrosis

Abstract Background A feature of myeloproliferative neoplasia is transforming to more aggressive and malignant myeloid neoplasia, including acute myeloid leukemia. Different pathogenesis mechanisms participate in transformation, including transformation of existing potential preleukemic clones, sinc...

Full description

Bibliographic Details
Main Authors: Marte Karen Brattås, Kyrre Lilleeng, Randi Hovland, Ingvild Jenssen Lægreid, Marta Vorland, Friedemann Leh, Øystein Bruserud, Bjørn Tore Gjertsen, Håkon Reikvam
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Biomarker Research
Subjects:
Primary myelofibrosis
AML
JAK2
Philadelphia chromosome
Clonal evolution
Online Access:http://link.springer.com/article/10.1186/s40364-018-0147-6

Internet

http://link.springer.com/article/10.1186/s40364-018-0147-6

Similar Items