Nox4 promotes endothelial differentiation through chromatin remodeling

Rationale: Nox4 is a constitutively active NADPH oxidase that constantly produces low levels of H2O2. Thereby, Nox4 contributes to cell homeostasis and long-term processes, such as differentiation. The high expression of Nox4 seen in endothelial cells contrasts with the low abundance of Nox4 in stem...

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Bibliographic Details
Main Authors: F. Hahner, F. Moll, T. Warwick, D.M. Hebchen, G.K. Buchmann, J. Epah, W. Abplanalp, T. Schader, S. Günther, R. Gilsbach, R.P. Brandes, K. Schröder
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Redox Biology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001537