Nonlinear DNA methylation trajectories in aging male mice

Nonlinear DNA methylation trajectories in aging male mice

Abstract Although DNA methylation data yields highly accurate age predictors, little is known about the dynamics of this quintessential epigenomic biomarker during lifespan. To narrow the gap, we investigate the methylation trajectories of male mouse colon at five different time points of aging. Our...

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Bibliographic Details
Main Authors: Maja Olecka, Alena van Bömmel, Lena Best, Madlen Haase, Silke Foerste, Konstantin Riege, Thomas Dost, Stefano Flor, Otto W. Witte, Sören Franzenburg, Marco Groth, Björn von Eyss, Christoph Kaleta, Christiane Frahm, Steve Hoffmann
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-47316-2

Internet

https://doi.org/10.1038/s41467-024-47316-2

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