Cerebellar alterations in a model of Down syndrome: The role of the Dyrk1A gene

Cerebellar alterations in a model of Down syndrome: The role of the Dyrk1A gene

Down syndrome (DS) is characterized by a marked reduction in the size of the brain and cerebellum. These changes play an important role in the motor alterations and cognitive disabilities observed in this condition. The Ts65Dn (TS) mouse, the most commonly used model of DS, reflects many DS phenotyp...

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Bibliographic Details
Main Authors: Susana García-Cerro, Verónica Vidal, Sara Lantigua, Maria Teresa Berciano, Miguel Lafarga, Pedro Ramos-Cabrer, Daniel Padro, Noemí Rueda, Carmen Martínez-Cué
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Neurobiology of Disease
Subjects:
Down syndrome
Cerebellum
Ts65Dn
Dyrk1A
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117302802

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http://www.sciencedirect.com/science/article/pii/S0969996117302802

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