The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing

The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing

XPA-binding protein (XAB)-2 is the human homologue of the yeast pre-mRNA splicing factor Syf1. Here the authors use an in vivo biotinylation tagging approach to show XAB2’s role in DNA repair, RNA splicing and transcription during mammalian development.

Detalles Bibliográficos
Autores principales: Evi Goulielmaki, Maria Tsekrekou, Nikos Batsiotos, Mariana Ascensão-Ferreira, Eleftheria Ledaki, Kalliopi Stratigi, Georgia Chatzinikolaou, Pantelis Topalis, Theodore Kosteas, Janine Altmüller, Jeroen A. Demmers, Nuno L. Barbosa-Morais, George A. Garinis
Formato: Artículo
Lenguaje:English
Publicado: Nature Portfolio 2021-05-01
Colección:Nature Communications
Acceso en línea:https://doi.org/10.1038/s41467-021-23505-1

Internet

https://doi.org/10.1038/s41467-021-23505-1

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