A single-cell transcriptomic atlas of exercise-induced anti-inflammatory and geroprotective effects across the body

A single-cell transcriptomic atlas of exercise-induced anti-inflammatory and geroprotective effects across the body

Exercise benefits the whole organism, yet, how tissues across the body orchestrally respond to exercise remains enigmatic. Here, in young and old mice, with or without exercise, and exposed to infectious injury, we characterized the phenotypic and molecular adaptations to a 12-month exercise across...

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Bibliographic Details
Main Authors: Shuhui Sun, Shuai Ma, Yusheng Cai, Si Wang, Jie Ren, Yuanhan Yang, Jiale Ping, Xuebao Wang, Yiyuan Zhang, Haoteng Yan, Wei Li, Concepcion Rodriguez Esteban, Yan Yu, Feifei Liu, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Jing Qu, Guang-Hui Liu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:The Innovation
Subjects:
exercise
aging
inflammation
circadian clock
BMAL1
single-cell RNA sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2666675823000085

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http://www.sciencedirect.com/science/article/pii/S2666675823000085

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