Immunogenicity of a protective intradermal DNA vaccine against lassa virus in cynomolgus macaques

Immunogenicity of a protective intradermal DNA vaccine against lassa virus in cynomolgus macaques

Lassa virus (LASV) is a hemorrhagic fever virus of the Arenaviridae family with high rates of mortality and co-morbidities, including chronic seizures and permanent bilateral or unilateral deafness. LASV is endemic in West Africa and Lassa fever accounts for 10–16% of hospitalizations annually in pa...

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Bibliographic Details
Main Authors: Jingjing Jiang, Preeti Banglore, Kathleen A. Cashman, Connie S. Schmaljohn, Katherine Schultheis, Holly Pugh, Jacklyn Nguyen, Laurent M. Humeau, Kate E. Broderick, Stephanie J. Ramos
Format: Article
Language:English
Published: Taylor & Francis Group 2019-09-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
immunogenicity
dna vaccine
lassa virus
intradermal
electroporation
Online Access:http://dx.doi.org/10.1080/21645515.2019.1616499

Internet

http://dx.doi.org/10.1080/21645515.2019.1616499

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