Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III

Neutralization of Zika virus by germline-like human monoclonal antibodies targeting cryptic epitopes on envelope domain III

The Zika virus (ZIKV), a flavivirus transmitted by Aedes mosquitoes, has emerged as a global public health concern. Pre-existing cross-reactive antibodies against other flaviviruses could modulate immune responses to ZIKV infection by antibody-dependent enhancement, highlighting the importance of un...

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Bibliographic Details
Main Authors: Yanling Wu, Shun Li, Lanying Du, Chunyu Wang, Peng Zou, Binbin Hong, Mengjiao Yuan, Xiaonan Ren, Wanbo Tai, Yu Kong, Chen Zhou, Lu Lu, Xiaohui Zhou, Shibo Jiang, Tianlei Ying
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Emerging Microbes and Infections
Subjects:
cryptic epitope
human monoclonal antibodies
Zika virus
Online Access:https://www.tandfonline.com/doi/10.1038/emi.2017.79

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https://www.tandfonline.com/doi/10.1038/emi.2017.79

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