DNA methylation and 28-year cardiovascular disease risk in type 1 diabetes: the Epidemiology of Diabetes Complications (EDC) cohort study

DNA methylation and 28-year cardiovascular disease risk in type 1 diabetes: the Epidemiology of Diabetes Complications (EDC) cohort study

Abstract Background The potential for DNA methylation (DNAm) as an early marker for cardiovascular disease (CVD) and how such an association might differ by glycemic exposure has not been examined in type 1 diabetes, a population at increased CVD risk. We thus performed a prospective epigenome-wide...

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Bibliographic Details
Main Authors: Rachel G. Miller, Josyf C. Mychaleckyj, Suna Onengut-Gumuscu, Eleanor Feingold, Trevor J. Orchard, Tina Costacou
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Clinical Epigenetics
Subjects:
Type 1 diabetes
Epigenetics
DNA methylation
Cardiovascular disease
Coronary artery disease
Major adverse cardiovascular events
Online Access:https://doi.org/10.1186/s13148-023-01539-0

Internet

https://doi.org/10.1186/s13148-023-01539-0

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