DNase-capture reveals differential transcription factor binding modalities.

DNase-capture reveals differential transcription factor binding modalities.

We describe DNase-capture, an assay that increases the analytical resolution of DNase-seq by focusing its sequencing phase on selected genomic regions. We introduce a new method to compensate for capture bias called BaseNormal that allows for accurate recovery of transcription factor protection prof...

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Bibliographic Details
Main Authors: Daniel Kang, Richard Sherwood, Amira Barkal, Tatsunori Hashimoto, Logan Engstrom, David Gifford
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5746236?pdf=render

Internet

http://europepmc.org/articles/PMC5746236?pdf=render

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