Vaccination with a replication-defective cytomegalovirus vaccine elicits a glycoprotein B-specific monoclonal antibody repertoire distinct from natural infection

Vaccination with a replication-defective cytomegalovirus vaccine elicits a glycoprotein B-specific monoclonal antibody repertoire distinct from natural infection

Abstract Human Cytomegalovirus (HCMV) is the leading infectious congenital infection globally and the most common viral infection in transplant recipients, therefore identifying a vaccine for HCMV is a top priority. Humoral immunity is a correlate of protection for HCMV infection. The most effective...

Full description

Bibliographic Details
Main Authors: Sarah M. Valencia, Eric Rochat, Melissa J. Harnois, Maria Dennis, Helen S. Webster, Bhavna Hora, Amit Kumar, Hsuan-Yuan (Sherry) Wang, Leike Li, Daniel Freed, Ningyan Zhang, Zhiqiang An, Dai Wang, Sallie R. Permar
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00749-0

Internet

https://doi.org/10.1038/s41541-023-00749-0

Similar Items