Deletion of the Npr3 gene increases severity of acute lung injury in obese mice

Abstract Previous studies have shown that atrial natriuretic peptide (ANP) attenuates agonist‐induced pulmonary edema and that this effect may be mediated in part by the ANP clearance receptor, natriuretic peptide receptor‐C (NPR‐C). Obesity has been associated with lower plasma ANP levels due to in...

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Bibliographic Details
Main Authors: Brianna D. Guarino, Christopher D. Dado, Ashok Kumar, Julie Braza, Elizabeth O. Harrington, James R. Klinger
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Pulmonary Circulation
Subjects:
Online Access:https://doi.org/10.1002/pul2.12270