Dynamics of DNMT3A mutation and prognostic relevance in patients with primary myelodysplastic syndrome

Dynamics of DNMT3A mutation and prognostic relevance in patients with primary myelodysplastic syndrome

Abstract Background DNMT3A gene mutation has been associated with poor prognosis in acute myeloid leukemia, but its clinical implications in myelodysplastic syndrome (MDS) and dynamic changes during disease progression remain controversial. Results In this study, DNMT3A mutation was identified in 7....

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Bibliographic Details
Main Authors: Ming-En Lin, Hsin-An Hou, Cheng-Hong Tsai, Shang-Ju Wu, Yuan-Yeh Kuo, Mei-Hsuan Tseng, Ming-Chih Liu, Chia-Wen Liu, Wen-Chien Chou, Chien-Yuan Chen, Jih-Luh Tang, Ming Yao, Chi-Cheng Li, Shang-Yi Huang, Bor-Sheng Ko, Szu-Chun Hsu, Chien-Ting Lin, Hwei-Fang Tien
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Clinical Epigenetics
Subjects:
DNMT3A
Myelodysplastic syndrome
Prognosis
Paired samples
Online Access:http://link.springer.com/article/10.1186/s13148-018-0476-1

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http://link.springer.com/article/10.1186/s13148-018-0476-1

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