Lipocalin-2 Deficiency Reduces Hepatic and Hippocampal Triggering Receptor Expressed on Myeloid Cells-2 Expressions in High-Fat Diet/Streptozotocin-Induced Diabetic Mice

Lipocalin-2 Deficiency Reduces Hepatic and Hippocampal Triggering Receptor Expressed on Myeloid Cells-2 Expressions in High-Fat Diet/Streptozotocin-Induced Diabetic Mice

Background: Lipocalin-2 (LCN2) is an acute-phase protein that has been linked to insulin resistance, diabetes, and neuroinflammatory diseases. Triggering receptor expressed on myeloid cells-2 (TREM2) has been also implicated in microglia-mediated neuroinflammation. However, the potential role of LCN...

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Bibliographic Details
Main Authors: Hyun Joo Shin, Zhen Jin, Hyeong Seok An, Gyeongah Park, Jong Youl Lee, So Jeong Lee, Hye Min Jang, Eun Ae Jeong, Kyung Eun Kim, Jaewoong Lee, Dae Young Yoo, Gu Seob Roh
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Brain Sciences
Subjects:
lipocalin-2
TREM2
inflammation
diabetic mouse
Online Access:https://www.mdpi.com/2076-3425/12/7/878

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https://www.mdpi.com/2076-3425/12/7/878

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