Structure and Immunogenicity of the <i>Bordetella pertussis</i> LOS-Derived Oligosaccharides in the Endosomal-Like Pre-Processing Mice Model

Structure and Immunogenicity of the <i>Bordetella pertussis</i> LOS-Derived Oligosaccharides in the Endosomal-Like Pre-Processing Mice Model

Glycoproteins are processed endosomally prior to presentation to T cells and subsequent induction of specific antibodies. The sugar part of glycoconjugate may be degraded while the type of the process depends on the features of the particular structure. The generated carbohydrate epitopes may differ...

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Bibliographic Details
Main Authors: Sabina Koj, Karolina Ucieklak, Czeslaw Lugowski, Tomasz Niedziela
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Vaccines
Subjects:
<i>Bordetella pertussis</i>
lipooligosaccharide
core oligosaccharide
neoglycoconjugates
endosomal glycan processing
reactive nitrogen species
Online Access:https://www.mdpi.com/2076-393X/9/6/645

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https://www.mdpi.com/2076-393X/9/6/645

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