A novel algorithm identifies stress-induced alterations in mitochondrial connectivity and inner membrane structure from confocal images.
Mitochondria exist as a highly interconnected network that is exquisitely sensitive to variations in nutrient availability, as well as a large array of cellular stresses. Changes in length and connectivity of this network, as well as alterations in the mitochondrial inner membrane (cristae), regulat...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-06-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC5501662?pdf=render |