A novel algorithm identifies stress-induced alterations in mitochondrial connectivity and inner membrane structure from confocal images.

Mitochondria exist as a highly interconnected network that is exquisitely sensitive to variations in nutrient availability, as well as a large array of cellular stresses. Changes in length and connectivity of this network, as well as alterations in the mitochondrial inner membrane (cristae), regulat...

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Bibliographic Details
Main Authors: Mathieu Ouellet, Gérald Guillebaud, Valerie Gervais, David Lupien St-Pierre, Marc Germain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5501662?pdf=render