High Mycobacterium tuberculosis Bacillary Loads Detected by Tuberculosis Molecular Bacterial Load Assay in Patient Stool: a Potential Alternative for Nonsputum Diagnosis and Treatment Response Monitoring of Tuberculosis

High Mycobacterium tuberculosis Bacillary Loads Detected by Tuberculosis Molecular Bacterial Load Assay in Patient Stool: a Potential Alternative for Nonsputum Diagnosis and Treatment Response Monitoring of Tuberculosis

ABSTRACT Not all patients produce sputum, yet most available TB tests use sputum. We investigated the utility of a novel RNA-based quantitative test, the tuberculosis molecular bacterial load assay (TB-MBLA), for the detection and quantification of Mycobacterium tuberculosis in stool. Stools from 10...

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Bibliographic Details
Main Authors: Emmanuel Musisi, Abdul Sessolo, Sylvia Kaswabuli, Josephine Zawedde, Patrick Byanyima, Shariifah Kasinga, Ingvar Sanyu, Esther Uwimaana, Stanley Walimbwa, Joseph Olore, Willy Ssengooba, Christine Sekaggya, Moses L. Joloba, William Worodria, Laurence Huang, Stephen H. Gillespie, Derek J. Sloan, Wilber Sabiiti
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:Microbiology Spectrum
Subjects:
molecular bacterial load assay
molecular diagnostics
Mycobacterium tuberculosis
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02100-21

Internet

https://journals.asm.org/doi/10.1128/spectrum.02100-21

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