Gut DNA Virome Diversity and Its Association with Host Bacteria Regulate Inflammatory Phenotype and Neuronal Immunotoxicity in Experimental Gulf War Illness

Gut DNA Virome Diversity and Its Association with Host Bacteria Regulate Inflammatory Phenotype and Neuronal Immunotoxicity in Experimental Gulf War Illness

Gulf War illness (GWI) is characterized by the persistence of inflammatory bowel disease, chronic fatigue, neuroinflammation, headache, cognitive impairment, and other medically unexplained conditions. Results using a murine model show that enteric viral populations especially bacteriophages were al...

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Bibliographic Details
Main Authors: Ratanesh K. Seth, Rabia Maqsood, Ayan Mondal, Dipro Bose, Diana Kimono, LaRinda A. Holland, Patricia Janulewicz Lloyd, Nancy Klimas, Ronnie D. Horner, Kimberly Sullivan, Efrem S. Lim, Saurabh Chatterjee
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Viruses
Subjects:
gulf war illness
virome
microbiome
next-generation sequencing
intestinal inflammation
neuroinflammation
ribavirin
il6
Online Access:https://www.mdpi.com/1999-4915/11/10/968

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https://www.mdpi.com/1999-4915/11/10/968

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