Performance of whole-genome promoter nucleosome profiling of maternal plasma cell-free DNA for prenatal noninvasive prediction of fetal macrosomia: a retrospective nested case-control study in mainland China

Performance of whole-genome promoter nucleosome profiling of maternal plasma cell-free DNA for prenatal noninvasive prediction of fetal macrosomia: a retrospective nested case-control study in mainland China

Abstract Background Fetal macrosomia is common occurrence in pregnancy, which is associated with several adverse prognosis both of maternal and neonatal. While, the accuracy of prediction of fetal macrosomia is poor. The aim of this study was to develop a reliable noninvasive prediction classifier o...

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Bibliographic Details
Main Authors: Qianwen Lu, Zhiwei Guo, Jun Zhang, Ke Wang, Qi Tian, Siping Liu, Kun Li, Cailing Xu, Caimin Li, Zenglu Lv, Zhigang Zhang, Xuexi Yang, Fang Yang
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Pregnancy and Childbirth
Subjects:
Fetal macrosomia
Classifier
Cell-free DNA
Low-coverage whole-genome promoter profiling
Noninvasive prediction
Online Access:https://doi.org/10.1186/s12884-022-05027-w

Internet

https://doi.org/10.1186/s12884-022-05027-w

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