Mitochondrial TSPO Deficiency Triggers Retrograde Signaling in MA-10 Mouse Tumor Leydig Cells

The mitochondrial translocator protein (TSPO) has been shown to bind cholesterol with high affinity and is involved in mediating its availability for steroidogenesis. We recently reported that targeted <i>Tspo</i> gene deletion in MA-10 mouse tumor Leydig cells resulted in reduced cAMP-s...

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Bibliographic Details
Main Authors: Jinjiang Fan, Vassilios Papadopoulos
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/1/252