Immunotherapy with heat shock protein 96 to treat gliomas

Abstract Heat shock protein 96 (gp96) is a highly conserved protein in the endoplasmic reticulum. The functions of gp96 include promoting the oncogenesis and progression of glioma. In addition, tumor-derived gp96 can activate anti-tumor immune. Therefore, this protein was used to generate an anti-tu...

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Bibliographic Details
Main Authors: Chunzhao Li, Yifei Du, Yang Zhang, Nan Ji
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Chinese Neurosurgical Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41016-020-00211-3