Potential inhibition of SARS-CoV-2 infection and its mutation with the novel geldanamycin analogue: Ignaciomycin

Potential inhibition of SARS-CoV-2 infection and its mutation with the novel geldanamycin analogue: Ignaciomycin

The impact of novel coronavirus (SARS-CoV-2) is very high; its mutant variants provide a higher transmission rate. Due to many mutations in the omicron-variant, it can evade previously available neutralizing antibodies. The inhibitory effect of the novel compound “Ignaciomycin” was investigated usin...

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Bibliographic Details
Main Authors: Antony Stalin, Pachaiyappan Saravana Kumar, Balakrishnan Senthamarai Kannan, Rajamanikam Saravanan, Savarimuthu Ignacimuthu, Quan Zou
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Arabian Journal of Chemistry
Subjects:
SARS-CoV-2
Mutations
Ignaciomycin
Molecular docking
Dynamics simulation
Viral inhibitor
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223009553

Internet

http://www.sciencedirect.com/science/article/pii/S1878535223009553

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