Lysine-Specific Demethylase 1 Inhibitors: A Comprehensive Review Utilizing Computer-Aided Drug Design Technologies

Lysine-Specific Demethylase 1 Inhibitors: A Comprehensive Review Utilizing Computer-Aided Drug Design Technologies

Lysine-specific demethylase 1 (LSD1/KDM1A) has emerged as a promising therapeutic target for treating various cancers (such as breast cancer, liver cancer, etc.) and other diseases (blood diseases, cardiovascular diseases, etc.), owing to its observed overexpression, thereby presenting significant o...

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Bibliographic Details
Main Authors: Di Han, Jiarui Lu, Baoyi Fan, Wenfeng Lu, Yiwei Xue, Meiting Wang, Taigang Liu, Shaoli Cui, Qinghe Gao, Yingchao Duan, Yongtao Xu
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
LSD1/KDM1A inhibitor
computer-aided drug design
molecular docking
QSAR
molecular dynamics simulation
Online Access:https://www.mdpi.com/1420-3049/29/2/550

Internet

https://www.mdpi.com/1420-3049/29/2/550

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