Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase.
Malaria parasite transmission requires differentiation of male and female gametocytes into gametes within a mosquito following a blood meal. A mosquito-derived molecule, xanthurenic acid (XA), can trigger gametogenesis, but the signalling events controlling this process in the human malaria parasite...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-06-01
|
Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC2408617?pdf=render |