NANOBODIES: STRUCTURE, MANUFACTURING, APPLICATION (REVIEW)

Introduction. Single-domain antibodies (nanobodies) are composed of the heavy-chain variable domain only. Compared to conventional immunoglobulins G (IgG) nanobodies have such qualities as: high bioavailability, ability to bind epitopes that are difficult to reach, high solubility and thermal stabil...

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Bibliographic Details
Main Authors: A. V. Shatalova, A. S. Yakubova, V. V. Palimpsestov, I. B. Esmagambetov
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-02-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/643