NANOBODIES: STRUCTURE, MANUFACTURING, APPLICATION (REVIEW)
Introduction. Single-domain antibodies (nanobodies) are composed of the heavy-chain variable domain only. Compared to conventional immunoglobulins G (IgG) nanobodies have such qualities as: high bioavailability, ability to bind epitopes that are difficult to reach, high solubility and thermal stabil...
Main Authors: | A. V. Shatalova, A. S. Yakubova, V. V. Palimpsestov, I. B. Esmagambetov |
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Format: | Article |
Language: | Russian |
Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-02-01
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Series: | Разработка и регистрация лекарственных средств |
Subjects: | |
Online Access: | https://www.pharmjournal.ru/jour/article/view/643 |
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