Predicting AURKA as a novel therapeutic target for NPC: A comprehensive analysis based on bioinformatics and validation

Predicting AURKA as a novel therapeutic target for NPC: A comprehensive analysis based on bioinformatics and validation

This study comprehensively explored the clinical function of Aurora kinase A (AURKA) gene in nasopharyngeal carcinoma (NPC) and analyzed its potential as a therapeutic target in cancer. Data were downloaded from GEO, STRING, GTEx, and CellMiner databases, and subjected to multiple bioinformatic anal...

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Bibliographic Details
Main Authors: Chaobin Huang, Lin Chen, Yiping Zhang, Liyan Wang, Wei Zheng, Fengying Peng, Yuanji Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
AURKA
nasopharyngeal carcinoma
therapeutic targets
cell cycle
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.926546/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.926546/full

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