Design of a large-scale femtoliter droplet array for single-cell analysis of drug-tolerant and drug-resistant bacteria

Design of a large-scale femtoliter droplet array for single-cell analysis of drug-tolerant and drug-resistant bacteria

Single-cell analysis is a powerful method to assess the heterogeneity among individual cells, enabling the identification of very rare cells with properties that differ from those of the majority. In this Methods Article, we describe the use of a large-scale femtoliter droplet array to enclose, isol...

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Bibliographic Details
Main Authors: Ryota eIino, Yoshimi eMatsumoto, Kunihiko eNishino, Akihito eYamaguchi, Hiroyuki eNoji
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Microbiology
Subjects:
Drug Resistance
Drug Tolerance
Single-Cell Analysis
transporter
drug efflux
Microdevice
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00300/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00300/full

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