Design of a large-scale femtoliter droplet array for single-cell analysis of drug-tolerant and drug-resistant bacteria
Single-cell analysis is a powerful method to assess the heterogeneity among individual cells, enabling the identification of very rare cells with properties that differ from those of the majority. In this Methods Article, we describe the use of a large-scale femtoliter droplet array to enclose, isol...
Main Authors: | Ryota eIino, Yoshimi eMatsumoto, Kunihiko eNishino, Akihito eYamaguchi, Hiroyuki eNoji |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2013-10-01
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Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2013.00300/full |
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