Disparities in spatially variable gene calling highlight the need for benchmarking spatial transcriptomics methods
Abstract Identifying spatially variable genes (SVGs) is a key step in the analysis of spatially resolved transcriptomics data. SVGs provide biological insights by defining transcriptomic differences within tissues, which was previously unachievable using RNA-sequencing technologies. However, the inc...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-09-01
|
Series: | Genome Biology |
Online Access: | https://doi.org/10.1186/s13059-023-03045-1 |