Effects of high-fat diet and AMP-activated protein kinase modulation on the regulation of whole-body lipid metabolism

Metabolic flexibility, the capacity to adapt to fuel availability for energy production, is crucial for maintaining whole-body energy homeostasis. An inability to adequately promote FA utilization is associated with lipid accumulation in peripheral tissues and contributes to the development of insul...

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Bibliographic Details
Main Authors: Milena Schönke, Julie Massart, Juleen R. Zierath
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520330844