Bioreactor-grown exo- and endo-β-glucan from Malaysian Ganoderma lucidum: An in vitro and in vivo study for potential antidiabetic treatment

Bioreactor-grown exo- and endo-β-glucan from Malaysian Ganoderma lucidum: An in vitro and in vivo study for potential antidiabetic treatment

This study aims to identify the roles of exo-β-glucan (EPS-BG) and endo-β-glucan (ENS-BG) extracted from Ganoderma lucidum (GL) in inhibiting the alpha-glucosidase enzyme, a target mechanism for postprandial hyperglycaemia regulation. Upscale production of GL was carried out using a 10 L bioreactor....

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Bibliographic Details
Main Authors: Nur Raihan Abdullah, Mohd Hamzah Mohd Nasir, Nur Hafizah Azizan, Wan Abd Al Qadr Imad Wan-Mohtar, Faez Sharif
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Ganoderma lucidum
alpha-glucosidase
polysaccharide
embryo toxicity test
zebrafish
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.960320/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2022.960320/full

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