eQTL mapping of rare variant associations using RNA-seq data: An evaluation of approaches.

Expression quantitative trait loci (eQTL) provide insight on transcription regulation and illuminate the molecular basis of phenotypic outcomes. High-throughput RNA sequencing (RNA-seq) is becoming a popular technique to measure gene expression abundance. Traditional eQTL mapping methods for microar...

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Bibliographic Details
Main Authors: Sharon Marie Lutz, Annie Thwing, Tasha Fingerlin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0223273