Integrating Peak Colocalization and Motif Enrichment Analysis for the Discovery of Genome-Wide Regulatory Modules and Transcription Factor Recruitment Rules

Integrating Peak Colocalization and Motif Enrichment Analysis for the Discovery of Genome-Wide Regulatory Modules and Transcription Factor Recruitment Rules

Chromatin immunoprecipitation followed by next-generation sequencing (ChIP-Seq) has opened new avenues of research in the genome-wide characterization of regulatory DNA-protein interactions at the genetic and epigenetic level. As a consequence, it has become the de facto standard for studies on the...

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Bibliographic Details
Main Authors: Mirko Ronzio, Federico Zambelli, Diletta Dolfini, Roberto Mantovani, Giulio Pavesi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Genetics
Subjects:
ChIP-seq
colocalization analysis
transcription factor (TF)
transcriptional regulation
transcription factor binding sites (TFBS)
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00072/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00072/full

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