Genetic Characterization and Population Structure of Drug-Resistant <i>Mycobacterium tuberculosis</i> Isolated from Brazilian Patients Using Whole-Genome Sequencing

Genetic Characterization and Population Structure of Drug-Resistant <i>Mycobacterium tuberculosis</i> Isolated from Brazilian Patients Using Whole-Genome Sequencing

The present study aimed to determine the genetic diversity of isolates of <i>Mycobacterium tuberculosis</i> (Mtb) from presumed drug-resistant tuberculosis patients from several states of Brazil. The isolates had been submitted to conventional drug susceptibility testing for first- and s...

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Main Authors: Leonardo Souza Esteves, Lia Lima Gomes, Daniela Brites, Fátima Cristina Onofre Fandinho, Marcela Bhering, Márcia Aparecida da Silva Pereira, Emilyn Costa Conceição, Richard Salvato, Bianca Porphirio da Costa, Reginalda Ferreira de Melo Medeiros, Paulo Cesar de Souza Caldas, Paulo Redner, Margareth Pretti Dalcolmo, Vegard Eldholm, Sebastien Gagneux, Maria Lucia Rossetti, Afrânio Lineu Kritski, Philip Noel Suffys
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Antibiotics
Subjects:
<i>Mycobacterium tuberculosis</i>
drug resistance
whole-genome sequencing
genetic diversity
Brazil
novel mutations
Online Access:https://www.mdpi.com/2079-6382/13/6/496

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https://www.mdpi.com/2079-6382/13/6/496

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