Proteomic Profiling of Iron Overload-Induced Human Hepatic Cells Reveals Activation of TLR2-Mediated Inflammatory Response

Proteomic Profiling of Iron Overload-Induced Human Hepatic Cells Reveals Activation of TLR2-Mediated Inflammatory Response

Background: Hepatic iron overload is common in patients who have undergone hematopoietic cell transplantation (HCT) and may predispose to peri- and post-HCT toxicity. To better reveal more molecules that might be involved in iron overload-induced liver injury, we utilized proteomics to investigate d...

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Bibliographic Details
Main Authors: Xiang Li, Shiwei Li, Mize Lu, Guohua Yang, Yunfeng Shen, Xin Zhou
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Molecules
Subjects:
iron overload
proteomics
TLR2
IL-6
NF-κB
Online Access:http://www.mdpi.com/1420-3049/21/3/322

Internet

http://www.mdpi.com/1420-3049/21/3/322

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