Incorporation of Escherichia coli heat-labile enterotoxin B subunit into rabies virus particles enhances its immunogenicity in mice and dogs

Incorporation of Escherichia coli heat-labile enterotoxin B subunit into rabies virus particles enhances its immunogenicity in mice and dogs

Although inactivated vaccines against rabies have the advantage of high safety, effective protection against rabies virus (RABV) infection often requires multiple, high-dose immunization. Incorporating a molecular adjuvant into the viral particles has been found to be a useful strategy to promote th...

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Bibliographic Details
Main Authors: Zhiyuan Gong, Hailun Li, Meichen Qian, Yujie Bai, Hongli Jin, Jingxuan Sun, Mengyao Zhang, Cuicui Jiao, Pei Huang, Yuanyuan Li, Haili Zhang, Hualei Wang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Biosafety and Health
Subjects:
RABV
Inactivated vaccine
Incorporation
LTB
Dendritic cells
Activation
Online Access:http://www.sciencedirect.com/science/article/pii/S2590053623000551

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http://www.sciencedirect.com/science/article/pii/S2590053623000551

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