Comprehensive behavioral analysis of indoleamine 2,3‐dioxygenase knockout mice
Abstract Aim Indoleamine 2,3‐dioxygenase 1 (IDO1) metabolizes the essential amino acid tryptophan into kynurenine derivatives, which are involved in neural activity via the kynurenine pathway (KP). IDO1 is an initial rate‐limiting enzyme in the KP and is activated by stress and/or inflammation. The...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-09-01
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| Series: | Neuropsychopharmacology Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/npr2.12019 |