Altered Signaling Pathways Revealed by Comprehensive Genomic Profiling in Patients With Unknown Primary Tumors

Altered Signaling Pathways Revealed by Comprehensive Genomic Profiling in Patients With Unknown Primary Tumors

PurposeCarcinoma of unknown primary (CUP) is a clinically aggressive disorder with early tumor dissemination. Identifying molecular traits of CUP can be not only beneficial for a better therapeutic approach but also potentially valuable for patients with general metastatic dissemination.Patients and...

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Bibliographic Details
Main Authors: Zhen Yang, Wei Cui, Ruoying Yu, Xinhua Dong, Jian Zhao, Lu Dai, Qiuxiang Ou, Hua Bao, Xue Wu, Chuanxin Wu, Jinhuo Lai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Oncology
Subjects:
carcinoma unknown primary
DNA damage repair
targeted therapy
homologous recombinant repair
clinically actionable mutation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.753311/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.753311/full

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