ROS-responsive PPGF nanofiber membrane as a drug delivery system for long-term drug release in attenuation of osteoarthritis

Abstract Excessive reactive oxygen species (ROS) are one of the leading mechanisms in the initiation and development of osteoarthritis (OA). However, conventional injection of ROS-responsive drug delivery systems (DDSs) such as nanoparticles and hydrogels usually cannot provide effective treatment d...

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Bibliographic Details
Main Authors: Jianjun Wu, Zainen Qin, Xianfang Jiang, Depeng Fang, Zhenhui Lu, Li Zheng, Jinmin Zhao
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-022-00254-3