Long-read based de novo assembly of low-complexity metagenome samples results in finished genomes and reveals insights into strain diversity and an active phage system

Long-read based de novo assembly of low-complexity metagenome samples results in finished genomes and reveals insights into strain diversity and an active phage system

Abstract Background Complete and contiguous genome assemblies greatly improve the quality of subsequent systems-wide functional profiling studies and the ability to gain novel biological insights. While a de novo genome assembly of an isolated bacterial strain is in most cases straightforward, more...

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Bibliographic Details
Main Authors: Vincent Somerville, Stefanie Lutz, Michael Schmid, Daniel Frei, Aline Moser, Stefan Irmler, Jürg E. Frey, Christian H. Ahrens
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Microbiology
Subjects:
Metagenomics
Whole genome sequencing
Finished metagenome-assembled genomes (MAGs)
de novo genome assembly
Natural whey cultures
Strain variation
Online Access:http://link.springer.com/article/10.1186/s12866-019-1500-0

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http://link.springer.com/article/10.1186/s12866-019-1500-0

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