Focal Management of Large Brain Metastases and Risk of Leptomeningeal Disease

Purpose: Surgery is often used for large or symptomatic brain metastases but is associated with risk of developing leptomeningeal dissemination. Emerging data suggest that fractionated stereotactic radiation therapy (FSRT) is an effective management strategy in large brain metastases. We sought to r...

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Bibliographic Details
Main Authors: Samuel R. Marcrom, MD, Paul M. Foreman, MD, Tyler B. Colvin, BS, Andrew M. McDonald, MD, MS, Robert S. Kirkland, MD, Richard A. Popple, PhD, Kristen O. Riley, MD, James M. Markert, MD, MPH, Christopher D. Willey, MD, PhD, Markus Bredel, MD, PhD, John B. Fiveash, MD
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Advances in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2452109419301034