Exposure-Response and Clinical Outcome Modeling of Inhaled Budesonide/Formoterol Combination in Asthma Patients

Exposure-Response and Clinical Outcome Modeling of Inhaled Budesonide/Formoterol Combination in Asthma Patients

Exposure-response and clinical outcome (CO) model for inhaled budesonide/formoterol was developed to quantify the relationship among pharmacokinetics (PK), pharmacodynamics (PD) and CO of the drugs and evaluate the covariate effect on model parameters. Sputum eosinophils cationic proteins (ECP) and...

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Bibliographic Details
Main Authors: Hyun-moon Back, Jong Bong Lee, Anhye Kim, Seon-Jong Park, Junyeong Kim, Jung-woo Chae, Seung Soo Sheen, Leonid Kagan, Hae-Sim Park, Young-Min Ye, Hwi-yeol Yun
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Pharmaceutics
Subjects:
moderate asthma
population analysis
budesonide/formoterol
asthma control test
dose optimization
Online Access:https://www.mdpi.com/1999-4923/12/4/336

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https://www.mdpi.com/1999-4923/12/4/336

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