CC16 drives VLA-2-dependent SPLUNC1 expression

CC16 drives VLA-2-dependent SPLUNC1 expression

RationaleCC16 (Club Cell Secretory Protein) is a protein produced by club cells and other non-ciliated epithelial cells within the lungs. CC16 has been shown to protect against the development of obstructive lung diseases and attenuate pulmonary pathogen burden. Despite recent advances in understand...

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Bibliographic Details
Main Authors: Natalie Iannuzo, Holly Welfley, Nicholas C. Li, Michael D. L. Johnson, Joselyn Rojas-Quintero, Francesca Polverino, Stefano Guerra, Xingnan Li, Darren A. Cusanovich, Paul R. Langlais, Julie G. Ledford
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
CC16
mycoplasma pneumoniae
SPLUNC1
airway epithelia
mass spectrometry
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1277582/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1277582/full

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