Sequence analysis of the non-coding control region of John Cunningham virus isolates from patients with multiple sclerosis treated with natalizumab

Introduction. The John Cunningham virus (JCPyV) causes a fatal demyelinating disease of the central nervous system known as progressive multifocal leukoencephalopathy (PML). In healthy people, the JCPyV non-coding control region (NCCR) is not rearranged, while NCCRs in immunocompromised patients are...

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Bibliographic Details
Main Authors: Marina A. Tyumentseva, Aleksandr I. Tyumentsev, Maria N. Zakharova, Lola S. Askarova, Taras O. Simaniv, Mikhail A. Piradov, Vasily G. Akimkin
Format: Article
Language:Russian
Published: Central Research Institute for Epidemiology 2023-04-01
Series:Журнал микробиологии, эпидемиологии и иммунобиологии
Subjects:
Online Access:https://microbiol.crie.ru/jour/article/viewFile/4739/841