Towards a Precision Medicine Approach and In Situ Vaccination against Prostate Cancer by PSMA-Retargeted oHSV

Towards a Precision Medicine Approach and In Situ Vaccination against Prostate Cancer by PSMA-Retargeted oHSV

Prostate specific membrane antigen (PSMA) is a specific high frequency cell surface marker of prostate cancers. Theranostic approaches targeting PSMA show no major adverse effects and rule out off-tumor toxicity. A PSMA-retargeted oHSV (R-405) was generated which both infected and was cytotoxic excl...

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Bibliographic Details
Main Authors: Andrea Vannini, Federico Parenti, Daniela Bressanin, Catia Barboni, Anna Zaghini, Gabriella Campadelli-Fiume, Tatiana Gianni
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Viruses
Subjects:
oncolytic virus
oncolytic herpes simplex virus
retargeting
PSMA
prostate cancer
vaccination
Online Access:https://www.mdpi.com/1999-4915/13/10/2085

Internet

https://www.mdpi.com/1999-4915/13/10/2085

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