Cell-permeable bone morphogenetic protein 2 facilitates bone regeneration by promoting osteogenesis

Cell-permeable bone morphogenetic protein 2 facilitates bone regeneration by promoting osteogenesis

The use of the FDA-approved osteoinductive growth factor BMP2 is widespread for bone regeneration. However, its clinical application has been hindered by limitations in cell permeability and a short half-life in circulation. To address this issue, we have developed a modified version of BMP2, referr...

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Bibliographic Details
Main Authors: Mingu Kang, Seokwon Lee, Jong-pil Seo, Eun-bee Lee, Daye Ahn, Jisoo Shin, Young-Ki Paik, Daewoong Jo
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Materials Today Bio
Subjects:
Bone morphogenetic protein
Advanced macromolecule transduction domain
Cell permeability
Osteogenesis
Osteogenic agent
Biobetter
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424000425

Internet

http://www.sciencedirect.com/science/article/pii/S2590006424000425

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