Structure Elucidation of Two Intriguing Neo-Debromoaplysiatoxin Derivatives from Marine Cyanobacterium <i>Lyngbya</i> sp. Showing Strong Inhibition of Kv1.5 Potassium Channel and Differential Cytotoxicity

Structure Elucidation of Two Intriguing Neo-Debromoaplysiatoxin Derivatives from Marine Cyanobacterium <i>Lyngbya</i> sp. Showing Strong Inhibition of Kv1.5 Potassium Channel and Differential Cytotoxicity

Two aplysiatoxin derivatives, neo-debromoaplysiatoxin I (<b>1</b>) and neo-debromoaplysiatoxin J (<b>2</b>), were isolated from marine cyanobacterium <i>Lyngbya</i> sp. collected from the South China Sea. Their structures including absolute configurations were ass...

Full description

Bibliographic Details
Main Authors: Zijun Chen, Na Chen, Peng Fu, Weiping Wang, Shilin Bian, Huihui Zhang, Sicheng Shen, Bingnan Han
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
cyanobacteria
<i>Lyngbya</i> sp.
aplysiatoxins
peroxide bridge
DP4+
Kv1.5 inhibition
Online Access:https://www.mdpi.com/1420-3049/28/6/2786

Internet

https://www.mdpi.com/1420-3049/28/6/2786

Similar Items